Condom Effectiveness in Heterosexual HIV Prevention

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By Gatopardo95 on Friday, February 11, 2005 - 10:26 pm:  Edit

The study below seems to be the most applicable that I have seen for heterosexual HIV transmission with and without condoms. You can read the data for yourself (sample was a bit small), but methodology was great.

The study consisted exclusively of heterosexual couples where one partner was HIV+ and the other was HIV-. One group used condoms 100% of the time during intercourse. The other group used it 0% of the time.

Extrapolating for 100 person years of intercourse, you had about a 1.14% chance of contracting HIV if you used condoms and a 5.75% chance of contracting HIV if you did not.

The one thing they didn't do was break it down by sex, but since Female to Male transmission is 2-10 times less likely than male to female transmission, you can draw your conclusions.

So condoms are effective in preventing heterosexual transmission, but we are talking about a very low risk either way.

If I interpret the data correctly, if you had heterosexual sex for a year with an HIV+ person you'd had a 0.0575% chance of geting HIV if you didn't wear a condom and 0.0114% if you did. With the chance of male to female transmission being somewhat higher and female to male being somewhat smaller.


Condom effectiveness in reducing heterosexual HIV transmission (Cochrane Review)
Weller S, Davis, K.


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A substantive amendment to this systematic review was last made on 19 November 2001. Cochrane reviews are regularly checked and updated if necessary.
Background: The amount of protection that condoms provide for HIV and other sexually transmitted infections is unknown. Cohort studies of sexually active HIV serodiscordant couples with follow-up of the seronegative partner, provide a situation in which a seronegative partner has known exposure to the disease and disease incidence can be estimated. When some individuals use condoms and some do not, namely some individuals use condoms 100% of the time and some never use (0%) condoms, condom effectiveness can be estimated by comparing the two incidence rates. Condom effectiveness is the proportionate reduction in disease due to the use of condoms.

Objectives: The objective of this review is to estimate condom effectiveness in reducing heterosexual transmission of HIV.

Search strategy: Studies were located using electronic databases (AIDSLINE, CINAHL, Embase, and MEDLINE) and handsearched reference lists.

Selection criteria: For inclusion, studies had to have: (1) data concerning sexually active HIV serodiscordant heterosexual couples, (2) a longitudinal study design, (3) HIV status determined by serology, and (4) contain condom usage information on a cohort of always (100%) or never (0%) condom users.

Data collection and analysis: Studies identified through the above search strategy that met the inclusion criteria were reviewed for inclusion in the analysis. Sample sizes, number of seroconversions, and the person-years of disease-free exposure time were recorded for each cohort. If available, the direction of transmission in the cohort (male-to-female, female-to-male), date of study enrollment, source of infection in the index case, and the presence of other STDs was recorded. Duplicate reports on the same cohort and studies with incomplete or nonsepecific information were excluded. HIV incidence was estimated from the cohorts of "always" users and for the cohorts of "never" users. Effectiveness was estimated from these two incidence estimates.

Main results: Of the 4709 references that were initially identified, 14 were included in the final analysis. There were 13 cohorts of "always" users that yielded an homogeneous HIV incidence estimate of 1.14 [95% C.I.: .56, 2.04] per 100 person-years. There were 10 cohorts of "never" users that appeared to be heterogeneous. The studies with the longest follow-up time, consisting mainly of studies of partners of hemophiliac and transfusion patients, yielded an HIV incidence estimate of 5.75 [95% C.I.: 3.16, 9.66] per 100 person-years. Overall effectiveness, the proportionate reduction in HIV seroconversion with condom use, is approximately 80%.

Authors' conclusions: This review indicates that consistent use of condoms results in 80% reduction in HIV incidence. Consistent use is defined as using a condom for all acts of penetrative vaginal intercourse. Because the studies used in this review did not report on the "correctness" of use, namely whether condoms were used correctly and perfectly for each and every act of intercourse, effectiveness and not efficacy is estimated. Also, this estimate refers in general to the male condom and not specifically to the latex condom, since studies also tended not to specify the type of condom that was used. Thus, condom effectiveness is similar to, although lower than, that for contraception.

Citation: Weller S, Davis, K.. Condom effectiveness in reducing heterosexual HIV transmission. The Cochrane Database of Systematic Reviews 2002, Issue 1. Art. No.: CD003255. DOI: 10.1002/14651858.CD003255.


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